CELVIVO BIOARRAY MATRIX DRIVE

Our cells are grown using the clinostat principle. We form three-dimensional spheroids, and then we incubate them for weeks until they become functional “synthetic organs” (see video below).

The Sidoli lab is the United States Center of Excellence for the company CelVivo, i.e. the company producing the ClinoStar incubator we use to produce the spheroids. Our lab provides training, external support, and we can also generate spheroids as fee-for-service. Feel free to contact us (link).

We create microsize spheroids and then we incubate them in the CelVivo bioreactor. After 20 days, the cells stop proliferating and acquire functional properties close to original solid tissues. This way we can produce more accurate models of living tissues in a cell lab.

The bioreactors we use (ClinoReactors) are very simple to maintain. Video below. It is also possible to grow spheroids in hypoxia to model more accurately the level of oxygen of cells in live tissues.